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Surgical treatment is carried out along with conservative therapy. The surgeon's help consists in opening abscesses and phlegmon with further washing and pumping out the purulent contents. In advanced cases, excision of adhesions is used.
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Actinomycosis in humans is caused by radiant fungi actinomycetes. Actinomycetes have similarities with generic viagra pills and bacteria, therefore they are isolated in an independent group 17. They are similar to bacteria in the presence of a nucleoid. They are united with mushrooms by a filamentous structure, which, intertwining, forms a mycelium. Some actinomycetes reproduce by spores, which also makes them related to fungi. Actinomycosis occurs in all countries of the world.
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Causes and causative agent of actinomycosis.
Actinomycetes are very stable in the environment and are widely distributed in nature.
They can be found in the soil, on spikelets of grain crops, in dust, on damp walls.
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In the endogenous way of development, actinomycosis in humans occurs when the opportunistic microflora is activated with a decrease in the body's immune defense (immunodeficiency states, vitamin deficiencies, debilitating long-term diseases, etc.).
Infection with a radiant fungus is possible when swallowing spores of actinomycetes located on plants, for example, due to the habit of biting a straw. Actinomycetes can also enter the human body during the threshing of cereal crops, by inhalation of dust containing radiant fungus. This is an exogenous route of infection by actinomycetes.
After the introduction of the fungus into the tissue, a seal (granuloma) is formed, inside which tissue dies (necrosis). In the center of the granuloma, the active development of the fungus occurs. A violent inflammatory reaction develops around the granuloma.
After softening, due to necrosis of the contents of the granuloma,t breakthrough of its contents into the surrounding tissues with the formation of fistulas. The contents of the granuloma can break into the lumen of the bronchial tree and, together with sputum, come out of the lungs when coughing. In such cases, the fungus can be found in the sputum.
The growth of the granuloma proceeds from the center of the lung to the periphery, with the involvement of the sheets of the visceral and then the parietal pleura with the development of an inflammatory reaction in them and the subsequent formation of adhesions between the sheets.
Actinomycosis of the skin can develop as a result of puncturing the skin with a straw, thorn and other sharp parts of the plant with the simultaneous introduction of actinomycetes into the wound.
At the beginning of its development, the infiltrate has a bluish color, but as it forms, it acquires a purple-red color. A softening area appears in the center of the infiltrate, which extends to the periphery of the infiltrate, a fluctuation symptom occurs. The content of the granuloma contains a large number of colonies (druse) of the radiant fungus.
The process becomes chronic. Foci of actinomycosis break out, into neighboring organs, i.e. fistulous passages are formed. The patient's condition is serious. General depletion of the body develops.
